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14 Seconds ago

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O uso de metformina diminuiu as taxas de mortalidade por qualquer causa em um estudo de pacientes com diabetes tipo 2, que tinham um alto risco de eventos cardiovasculares (CV), de acordo com os investigadores.⠀ ⠀ O tratamento com fármaco, no entanto, não reduziu as taxas de desfecho composto de morte CV, infarto do miocárdio ou acidente vascular cerebral isquêmico.⠀ ⠀ O achado é proveniente de uma análise post hoc do ensaio SAVOR-TIMI 53 e incluiu 12.156 pacientes que tinham amostras de biomarcadores de linha de base. Destes pacientes, 8971 (74%) tinham tomado metformina, 1611 (13%) tinham insuficiência cardíaca prévia e 1332 (11%) tinham pelo menos doença renal crônica moderada (DRC), definida como uma taxa de filtração glomerular estimada de 45 mL. / min / 1,73 m2 ou abaixo.⠀ ⠀ Embora o risco do desfecho composto fosse semelhante entre pacientes que já haviam usado metformina e aqueles que nunca o fizeram, o grupo metformina teve uma redução significativa de 25% no risco de morte por qualquer causa em análises ajustadas, Brian A. Bergmark, MD de Brigham e o Women's Hospital e a Harvard Medical School em Boston, e colegas relataram na Circulation.⠀ ⠀ Os pesquisadores não encontraram associação significativa entre esses desfechos e o uso de metformina entre pacientes com IC prévia ou DRC moderada a grave.⠀ ⠀ Em uma revisão sistemática anterior de 17 estudos observacionais publicados em Annals of Internal Medicine em 2017, os pesquisadores concluíram que o uso de metformina está associado à redução da mortalidade por todas as causas em pacientes com DRC, insuficiência cardíaca congestiva ou doença hepática crônica com insuficiência hepática.⠀ ⠀ Matéria completa na nossa página no facebook ⠀ ⠀ ⠀ #saude #endocrinologista #nutricao #vidasaudavel #saoluis #dracibelemagalhaes #ma

42 Seconds ago

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1 Minutes ago

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1 Minutes ago

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1 Minutes ago

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2 Minutes ago

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2 Minutes ago

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2 Minutes ago

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3 Minutes ago

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4 Minutes ago

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4 Minutes ago

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5 Minutes ago

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Buzzards bay-Got tanned ,play with Drone Brewing building- i liked the ambiance there Martha’s Vineyard by ferry- saw sweet houses,ate clam chowder and shrimp burger Also met Bill Murray I did kayaking for the first time.I’ll share you guys later 😺 I had a really good experience.i appreciate your kindness,Larry. #buzzardsbay #MA #US

6 Minutes ago

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7 Minutes ago

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7 Minutes ago

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8 Minutes ago

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8 Minutes ago

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11 Minutes ago

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12 Minutes ago

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12 Minutes ago